Structural heart disease (SHD) refers to diseases that affect structures of the heart's valves, walls, chambers, or muscles, and is common in daily cardiology practice. To offer the best therapeutic solution for patients, a multidisciplinary heart team with various heart specialists including interventional cardiologists, cardiothoracic surgeons, imaging cardiologists or radiologists, cardiac anesthesiologists, and nurse coordinators are often involved. Over the past decade, transcatheter treatment of structural heart has emerged as a part of standard treatment of structural heart disease. The continuous increase in operators' skills, further engineering refinements, of the devices, improving outcomes of transcatheter intervention, making transcatheter treatments a rapidly expanding field of contemporary therapy for SHD.  There are pros and cons of newly emerged transcatheter treatment options for SHD and diagnostic challenges remain in this field. It is a rapidly developing field in cardiovascular disease. For this reason, this Special Issue will focus on trends, challenges of diagnosis and treatment in structural heart disease.

Specific thoughts on topics:

Watchman/Amulex updates: sizing, outcome, pro and con, imaging roles;

Updates: TAVR, TAVR in older population, low gradient AS, Selection of SAVR and TAVR, TAVR for AR, imaging roles;

Mitral edge to edge repair: MitraClip system vs PASAL, indication, case selection, practical pearls, outcome update, imaging roles;

Transcatheter tricuspid therapy;

Upcoming new transcatheter procedures.