AccScience Publishing / GTM / Volume 2 / Issue 4 / DOI: 10.36922/gtm.2341
Submit to GTM
Cite this article
48
Download
569
Views
Journal Browser
Volume | Year
Issue
Search
Forthcoming Issue
Current Issue
View All
News and Announcements
View All
CASE REPORT

Management of persistent genital arousal disorder: A case report

Tainara Tavares Menchete1 ,  Rodolfo Silva Bertoli1 ,  Amanda Aguiar Loureiro1 ,  Ana Carolina Japur de Sá Rosa-e-Silva1 ,  Fabiola Dach1 ,  Julia Kefalás Troncon1 ,  Debora Aiesha Leite Cantelli1 ,  Lucia Alves da Silva Lara1*
Show Less
1 Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Global Translational Medicine 2023, 2(4), 2341 https://doi.org/10.36922/gtm.2341
Submitted: 30 November 2023 | Accepted: 12 December 2023 | Published: 26 December 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Download PDF
Cite
XML
Abstract

Persistent genital arousal disorder (PGAD) is a pathological condition characterized by intrusive, unwanted, and distressing symptoms related to spontaneous and prolonged sensations of genital arousal in the absence of sexual desire or stimulation that may compromise the individual’s quality of life. Here, we report the case of a woman who suffered from PGAD probably associated with multiple alterations in the spinal column and Tarlov cyst, which caused the compression of nerve roots and the abnormal sensitivity of the genital region.

Keywords
Orgasm
Sexual arousal
Arousal disorder
Funding
None.
References
  1. Facelle TM, Sadeghi-Nejad H, Goldmeier D, 2013, Persistent genital arousal disorder: characterization, etiology, and management. J Sex Med, 10: 439–450. https://doi.org/10.1111/j.1743-6109.2012.02990.x

 

  1. Jackowich RA, Pink L, Gordon A, et al., 2016, Persistent genital arousal disorder: A review of its conceptualizations, potential origins, impact, and treatment. Sex Med Rev, 4: 329–342. https://doi.org/10.1016/j.sxmr.2016.06.003

 

  1. Leiblum SR, Nathan SG, 2001, Persistent sexual arousal syndrome: A newly discovered pattern of female sexuality. J Sex Marital Ther, 27: 365–380. https://doi.org/10.1080/009262301317081115

 

  1. Pukall CF, Jackowich R, Mooney K, et al., 2019, Genital sensations in persistent genital arousal disorder: A case for an overarching nosology of genitopelvic dysesthesias? Sex Med Rev, 7: 2–12. https://doi.org/10.1016/j.sxmr.2018.08.001

 

  1. Jackowich RA, Pukall CF, 2020, Prevalence of persistent genital arousal disorder in 2 North American samples. J Sex Med, 17: 2408–2416. https://doi.org/10.1016/j.jsxm.2020.09.004

 

  1. Bedell S, Goldstein AT, Burrows L, 2014, A periclitoral mass as a cause of persistent genital arousal disorder. J Sex Med, 11: 136–139. https://doi.org/10.1111/jsm.12165

 

  1. Thorne C, Stuckey B, 2008, Pelvic congestion syndrome presenting as persistent genital arousal: A case report. J Sex Med, 5: 504–508. https://doi.org/10.1111/j.1743-6109.2007.00666.x

 

  1. Klifto KM, Dellon AL, 2020, Persistent genital arousal disorder: Review of pertinent peripheral nerves. Sex Med Rev, 8: 265–273. https://doi.org/10.1016/j.sxmr.2019.10.001

 

  1. Pink L, Rancourt V, Gordon A, 2014, Persistent genital arousal in women with pelvic and genital pain. J Obstet Gynaecol Can, 36: 324–330. https://doi.org/10.1016/S1701-2163(15)30608-3

 

  1. Oaklander AL, Sharma S, Kessler K, et al., 2020, Persistent genital arousal disorder: A special sense neuropathy. Pain Rep, 5: e801. https://doi.org/10.1097/PR9.0000000000000801

 

  1. Anzellotti F, Franciotti R, Bonanni L, et al., 2010, Persistent genital arousal disorder associated with functional hyperconnectivity of an epileptic focus. Neuroscience, 167: 88–96. https://doi.org/10.1016/j.neuroscience.2010.01.050

 

  1. Marino D, Carluccio MA, Di Donato I, et al., 2013, Tarlov cysts: clinical evaluation of an italian cohort of patients. Neurol Sci, 34: 1679–1682. https://doi.org/10.1007/s10072-013-1321-0

 

  1. Klepinowski T, Orbik W, Sagan L, 2021, Global incidence of spinal perineural Tarlov’s cysts and their morphological characteristics: A meta-analysis of 13,266 subjects. Surg Radiol Anat, 43: 855–863. https://doi.org/10.1007/s00276-020-02644-y

 

  1. Feigenbaum F, Boone K, 2015, Persistent genital arousal disorder caused by spinal meningeal cysts in the sacrum: Successful neurosurgical treatment. Obstet Gynecol, 126: 839–843. https://doi.org/10.1097/AOG.0000000000001060

 

  1. Leiblum SR, Goldmeier D, 2008, Persistent genital arousal disorder in women: case reports of association with anti-depressant usage and withdrawal. J Sex Marital Ther, 34: 150–159. https://doi.org/10.1080/00926230701636205

 

  1. Goldmeier D, Leiblum S, 2008, Interaction of organic and psychological factors in persistent genital arousal disorder in women: A report of six cases. Int J STD AIDS, 19: 488–490. https://doi.org/10.1258/ijsa.2007.007298

 

  1. Romanzi L, 2010, Techniques of pudendal nerve block. J Sex Med, 7: 1716–1719. https://doi.org/10.1111/j.1743-6109.2010.01822.x

 

  1. Jönsson EH, Backlund Wasling H, Wagnbeck V, et al., 2015, Unmyelinated tactile cutaneous nerves signal erotic sensations. J Sex Med, 12: 1338–1345. https://doi.org/10.1111/jsm.12905

 

  1. Cohen SD, 2017, Diagnosis and treatment of persistent genital arousal disorder. Rev Urol, 19: 265–267. https://doi.org/10.3909/riu0784

 

  1. Aoun F, Alkassis M, Tayeh GA, et al., 2021, Sexual dysfunction due to pudendal neuralgia: A systematic review. Transl Androl Urol, 10: 2500–2511. https://doi.org/10.21037/tau-21-13

 

  1. Goldstein I, Komisaruk BR, Pukall CF, et al., 2021, International society for the study of women’s sexual health (ISSWSH) review of epidemiology and pathophysiology, and a consensus nomenclature and process of care for the management of persistent genital arousal disorder/genito-pelvic dysesthesia (PGAD/GPD). J Sex Med, 18: 665–697. https://doi.org/10.1016/j.jsxm.2021.01.172

 

  1. Jackowich RA, Mooney KM, Hecht E, et al., 2021, Online pelvic floor group education program for women with persistent genital arousal disorder/genito-pelvic dysesthesia: Descriptive feasibility. JMIR Form Res, 5: e22450. https://doi.org/10.2196/22450

 

  1. Kruger THC, 2018, Can pharmacotherapy help persistent genital arousal disorder? Expert Opin Pharmacother, 19: 1705–1709. https://doi.org/10.1080/14656566.2018.1525359

 

  1. Subash P, Gray A, Boswell M, et al., 2023, A comparison of neuroelectrophysioçogy databases. Sci Data, 10: 719. https://doi.org/10.1038/s41597-023-02614-0
Conflict of interest
The authors declare that they have no competing interests.
Share
Back to top
Global Translational Medicine, Electronic ISSN: 2811-0021 Published by AccScience Publishing
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here
Accept