AccScience Publishing / ITPS / Volume 5 / Issue 1 / DOI: 10.36922/itps.287
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RESEARCH ARTICLE

 Formulation and Pharmacological Evaluation of Herbal Gel Containing Curcuma longa

Puja Kumari1* Souravh Bais1
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1 Institute of Pharmaceutical Sciences, Sage University, Indore, Madhya Pradesh, India
INNOSC Theranostics and Pharmacological Sciences 2022, 5(1), 1–6; https://doi.org/10.36922/itps.287
Submitted: 6 December 2022 | Accepted: 13 January 2023 | Published: 3 February 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

The aim of the present study is to formulate and evaluate a polyherbal gel that contains Curcuma longa extract. The ethanolic extract of C. longa’s rhizome was used to create a gel formulation in different concentrations (1, 2, 3, and 4%). Topical anti-inflammatory activity of gel was also assessed. Gel was prepared using Carbopol® 940 (1% w/v), C. longa extract, ethanol, propylene glycol 400, methyl paraben, propyl paraben, ethylenediaminetetraacetic acid, tri-ethanolamine, and the necessary amount of distilled water. The prepared formulations were assessed for their physical qualities, pH, spreadability, and ability to irritate skin to detect toxicity or side effects. The findings suggested that gel compositions were good in terms of appearance and uniformity.

Keywords
Herbal
Gel
Anti-inflammatory activity
Ethanolic extract of Curcuma longa
Funding
None.
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Conflict of interest
There is no conflict of interest in regards to the study.
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INNOSC Theranostics and Pharmacological Sciences, Electronic ISSN: 2705-0823 Published by AccScience Publishing