AccScience Publishing / JCTR / Online First / DOI: 10.36922/JCTR025480087
EDITORIAL

Major issues in translational medicine

Jacek Z. Kubiak1,2*
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1 Institute of Genetics and Development of Rennes, UMR 6290 CNRS/University of Rennes, Faculty of Medicine, 35043 Rennes, France
2 Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine-National Research Institute (WIM-PIB), Szaserow 128, 04-141 Warszawa, Poland
Received: 27 November 2025 | Accepted: 1 December 2025 | Published online: 9 December 2025
© 2025 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Conflict of interest
Jacek Z. Kubiak is the Editor-in-Chief of this journal. The author declares that he has no known competing financial interests or personal relationships that could have influenced the work reported in this paper.
References
  1. Loh JS, Low CY, Low WP, et al. Traversing the Valley of Death for nanotechnology-based natural products: Strategies and insights from pharmaceutical stakeholders. Drug Deliv Transl Res. 2025;15(11):4126-4140. doi: 10.1007/s13346-025-01923-8

 

  1. Failli V, Strittmatter SM, Schwab ME, et al. Crossing the valley of death in spinal cord injury: Learning from successful translators. Neurotrauma Rep. 2025;6(1):298-310. doi: 10.1089/neur.2025.0029

 

  1. Zhu H, Yu J, Luo J, Cai Z, Li L, Zheng Q. Development of a cross-species model to predict clinical outcomes based on efficacy in mouse models of non-alcoholic fatty liver disease. Clin Res Hepatol Gastroenterol. 2025;49(9):102702. doi: 10.1016/j.clinre.2025.102702

 

  1. Barroca NCB, Della Santa G, Suchecki D, García- Cairasco N, Umeoka EHL. Challenges in the use of animal models and perspectives for a translational view of stress and psychopathologies. Neurosci Biobehav Rev. 2022;140:104771. doi: 10.1016/j.neubiorev.2022.104771

 

  1. Ostrand-Rosenberg S. Animal models of tumor immunity, immunotherapy and cancer vaccines. Curr Opin Immunol. 2004;16(2):143-50. doi: 10.1016/j.coi.2004.01.003

 

  1. Ferreira RS Jr., Mantovani CK, Ferreira ASSBS, et al. Translational science at the undergraduate level: Awakening talents to overcome the valley of death - case report. J Venom Anim Toxins Incl Trop Dis. 2025;31:e20250005. doi: 10.1590/1678-9199-jvatitd-2025-0005

 

  1. Mir A, Zhu A, Lau R, et al. Applications, limitations, and considerations of clinical trials in a dish. Bioengineering (Basel). 2024;11(11):1096. doi: 10.3390/bioengineering11111096
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Journal of Clinical and Translational Research, Electronic ISSN: 2424-810X Print ISSN: 2382-6533, Published by AccScience Publishing