In recent years, telemedicine has emerged as a vital tool in the diagnosis, management, and treatment of psychosomatic disorders, offering increased accessibility and continuity of care. This special issue invites original research, reviews, and clinical reports that explore the effectiveness, limitations, and evolving challenges of telehealth interventions in the context of psychosomatic medicine. Topics may include clinical outcomes, patient engagement, technological barriers, ethical considerations, and innovations in digital mental health. We aim to highlight both the promise and complexity of integrating telemedicine into multidisciplinary care models for psychosomatic conditions.