AccScience Publishing / ITPS / Volume 6 / Issue 1 / DOI: 10.36922/itps.348
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RESEARCH ARTICLE

Cardiovascular Evaluation in Patients with Systemic Sclerosis in the Turkish Population

Tarik Kivrak1* Mehdi Karasu1 Ozkan Karaca1 Suleyman Serdar Koca2
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1 Department of Cardiology, Firat University, Elazig, Turkey
2 Department of Rheumatology, Firat University, Elazig, Turkey
INNOSC Theranostics and Pharmacological Sciences 2023, 6(1), 22–27; https://doi.org/10.36922/itps.348
Submitted: 31 January 2023 | Accepted: 21 March 2023 | Published: 5 April 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Cardiac involvement in systemic sclerosis (SSc) can lead to high morbidity and mortality. Therefore, early diagnosis and treatment are required. The aim of this study was to investigate the clinical, laboratory, and echocardiographic features of SSc, evaluate the proportion of patients with cardiovascular disease, and compare them with other population-based studies in the Turkish population. This study included 150 patients who were previously diagnosed and treated in the rheumatology clinic. Their age, sex, clinical signs and symptoms, laboratory and echocardiography findings, and concomitant diseases were evaluated. The results showed that the disease duration was <1 year and, at most, 11 years, with only one patient having elevated pulmonary artery pressure. In addition, patients with SSc in our region had similar demographic, clinical, laboratory, and echocardiographic features with those in other countries. This study demonstrated that hypertension is positively correlated with disease duration and the incidence of pulmonary hypertension is very low in patients with SSc.

Keywords
Systemic sclerosis
Cardiovascular disease
Scleroderma
Pulmonary hypertension
Hypertension
Funding
None.
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Conflict of interest
The authors declare no conflicts of interests.
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INNOSC Theranostics and Pharmacological Sciences, Electronic ISSN: 2705-0823 Published by AccScience Publishing