Dear Colleagues

Novel approaches in tissue engineering to generate tissue models for drug discovery and disease modelling or for the fabrication of tissue surrogates to replace injured human tissues have made significant progress in recent years. In parallel, new techniques in tissue-specific differentiation of induced pluripotent stem cells (iPSCs), trans-differentiation of mesenchymal stem cells, and in organoid technology and multi-organ fluidic chip devices have opened new avenues for modeling diseases and validating drug response in a patient-specific manner, thus contributing to patient-tailored therapies. The combination of these cell biological and biomedical techniques to mimic the human tissue microenvironment holds the promise to bridge the gap between cell line-based drug testing and applications in patients and thereby contributes to the reduction of whole animal experiments.

In this Special Issue of the International Journal of Bioprinting, we will highlight novel strategies in advanced tissue engineering and highly appreciate the submission of original research articles, reviews, commentaries or short reports in bioprinting, tissue engineering, organoids and organ-on-a-chip models especially in the fields of drug validation, toxicity testing and disease modelling.