AccScience Publishing / IJB / Volume 9 / Issue 6 / DOI: 10.36922/ijb.0112
Submit to IJB
Cite this article
471
Download
2221
Views
Journal Browser
Volume | Year
Issue
Search
Forthcoming Issue
Current Issue
View All
News and Announcements
View All
REVIEW

Organoid bioprinting strategy and application in biomedicine: A review

Chen He1 ,  Jiasheng Yan2 ,  Yusheng Fu1 ,  Jiuchuan Guo1 ,  Yuxing Shi1 ,  Jinhong Guo1,2*
Show Less
1 School of Information and Communication Engineering, University of Electronic Science and Technology of China, Chengdu, China
2 School of Sensing Science and Engineering, Shanghai Jiao Tong University, Shanghai, China
IJB 2023, 9(6), 0112 https://doi.org/10.36922/ijb.0112
Submitted: 3 April 2023 | Accepted: 16 May 2023 | Published: 30 June 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Download PDF
Cite
XML
Abstract

Organoids are three-dimensional cell structures cultured in vitro. They are self-organizing and can mimic real organs in structure and function. Bioprinting technology breaks through some limitations of organoid manufacturing, making it more widely used in drug screening, regenerative medicine, and other fields. In this review, we first introduce bioinks and bioprinting methods for stem cell and organoid bioprinting, then summarize several vascularization strategies for bioprinting organoids, and present applications in biomedicine. In the future, the development of microfluidic technology and four-dimensional bioprinting technology may be conducive to forming better bioprinted organoids.

Keywords
Bioprinting
Organoid
Tissue engineering
Funding
This work is funded by the financial support from National Natural Science Foundation of China (62122017).
References
  1. Lancaster MA, Knoblich JA, 2014, Organogenesis in a dish: Modeling development and disease using organoid technologies. Science, 345(6194): 1247125. https://doi.org/10.1126/science.1247125

 

 

  1. Hofer M, Lutolf MP, 2021, Engineering organoids. Nat Rev Mater, 6(5): 402–420. https://doi.org/10.1038/s41578-021-00279-y

 

 

  1. Zhao Z, Chen X, Dowbaj AM, et al., 2022, Organoids. Nat Rev Methods Primers, 2(1): 94. https://doi.org/10.1038/s43586-022-00174-y

 

 

  1. Sato T, Vries RG, Snippert HJ, et al., 2009, Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature, 459(7244): 262–265. https://doi.org/10.1038/nature07935

 

 

  1. Lewis-Israeli YR, Wasserman AH, Gabalski MA, et al., 2021, Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease. Nat Commun, 12(1): 5142. https://doi.org/10.1038/s41467-021-25329-5

 

 

  1. Hofbauer P, Jahnel SM, Papai N, et al., 2021, Cardioids reveal self-organizing principles of human cardiogenesis. Cell, 184(12): 3299–3317.e22. https://doi.org/10.1016/j.cell.2021.04.034

 

 

  1. Takasato M, Er PX, Chiu HS, et al., 2015, Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 526(7574): 564–568. https://doi.org/10.1038/nature15695

 

 

  1. Hu H, Gehart H, Artegiani B, et al., 2018, Long-term expansion of functional mouse and human hepatocytes as 3D organoids. Cell, 175(6): 1591–1606.e19. https://doi.org/10.1016/j.cell.2018.11.013

 

 

  1. Lancaster MA, Renner M, Martin C-A, et al., 2013, Cerebral organoids model human brain development and microcephaly. Nature, 501(7467): 373–379. https://doi.org/10.1038/nature12517

 

 

  1. Neal JT, Li X, Zhu J, et al., 2018, Organoid modeling of the tumor immune microenvironment. Cell, 175(7): 1972–1988.e16. https://doi.org/10.1016/j.cell.2018.11.021

 

 

  1. Monteil V, Kwon H, Prado P, et al., 2020, Inhibition of SARS-CoV-2 infections in engineered human tissues using clinical-grade soluble human ACE2. Cell, 181(4): 905–913.e7. https://doi.org/10.1016/j.cell.2020.04.004

 

 

  1. Han Y, Duan X, Yang L, et al., 2021, Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature, 589(7841): 270–275. https://doi.org/10.1038/s41586-020-2901-9

 

 

  1. Garreta E, Kamm RD, Chuva de Sousa Lopes SM, et al., 2021, Rethinking organoid technology through bioengineering. Nat Mater, 20(2): 145–155. https://doi.org/10.1038/s41563-020-00804-4

 

 

  1. Lawlor KT, Vanslambrouck JM, Higgins JW, et al., 2021, Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation. Nat Mater, 20(2): 260–271. https://doi.org/10.1038/s41563-020-00853-9

 

 

  1. Rawal P, Tripathi DM, Ramakrishna S, et al., 2021, Prospects for 3D bioprinting of organoids. Bio-Des Manuf, 4(3): 627–640. https://doi.org/10.1007/s42242-020-00124-1

 

 

  1. Gu Z, Fu J, Lin H, et al., 2020, Development of 3D bioprinting: From printing methods to biomedical applications. Asian J Pharm Sci, 15(5): 529–557. https://doi.org/10.1016/j.ajps.2019.11.003

 

 

  1. Gungor-Ozkerim PS, Inci I, Zhang YS, et al., 2018, Bioinks for 3D bioprinting: An overview. Biomater Sci, 6(5): 915–946. https://doi.org/10.1039/C7BM00765E

 

 

  1. Gu Q, Tomaskovic‐Crook E, Lozano R, et al., 2016, Functional 3D neural mini‐tissues from printed gel‐based bioink and human neural stem cells. Adv Healthc Mater, 5(12): 1429–1438. https://doi.org/10.1002/adhm.201600095

 

 

  1. Faulkner-Jones A, Fyfe C, Cornelissen D-J, et al., 2015, Bioprinting of human pluripotent stem cells and their directed differentiation into hepatocyte-like cells for the generation of mini-livers in 3D. Biofabrication, 7(4): 044102. https://doi.org/10.1088/1758-5090/7/4/044102

 

 

  1. Nguyen D, Hägg DA, Forsman A, et al., 2017, Cartilage tissue engineering by the 3D bioprinting of iPS cells in a nanocellulose/alginate bioink. Sci Rep, 7(1): 658. https://doi.org/10.1038/s41598-017-00690-y

 

 

  1. Sakai S, Ohi H, Hotta T, et al., 2018, Differentiation potential of human adipose stem cells bioprinted with hyaluronic acid/ gelatin-based bioink through microextrusion and visible light-initiated crosslinking. Biopolymers, 109(2): e23080. https://doi.org/10.1002/bip.23080

 

 

  1. Eswaramoorthy SD, Dhiman N, Joshi A, et al., 2021, 3D bioprinting of mesenchymal stem cells and endothelial cells in an alginate-gelatin-based bioink. J 3D Print Med, 5(1): 23–36. https://doi.org/10.2217/3dp-2020-0026

 

 

  1. Kolan KCR, Semon JA, Bromet B, et al., 2019, Bioprinting with human stem cells-laden alginate-gelatin bioink and bioactive glass for tissue engineering. Int J Bioprint, 5(2.2): 3–15. https://doi.org/10.18063/ijb.v5i2.2.204

 

 

  1. Ni T, Liu M, Zhang Y, et al., 2020, 3D bioprinting of bone marrow mesenchymal stem cell-laden silk fibroin double network scaffolds for cartilage tissue repair. Bioconjugate Chem, 31: 1938–1947. https://doi.org/10.1021/acs.bioconjchem.0c00298

 

 

 

 

  1. Das S, Pati F, Choi Y-J, et al., 2015, Bioprintable, cell-laden silk fibroin–gelatin hydrogel supporting multilineage differentiation of stem cells for fabrication of three-dimensional tissue constructs. Acta Biomater, 11: 233–246. https://doi.org/10.1016/j.actbio.2014.09.023

 

 

  1. Skardal A, Mack D, Kapetanovic E, et al., 2012, Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Translat Med, 1(11): 792–802. https://doi.org/10.5966/sctm.2012-0088

 

 

  1. Han J, Kim DS, Jang H, et al., 2019, Bioprinting of three-dimensional dentin–pulp complex with local differentiation of human dental pulp stem cells. J Tissue Eng, 10: 2041731419845849. https://doi.org/10.1177/2041731419845849

 

 

  1. Ren Y, Yang X, Ma Z, et al., 2021, Developments and opportunities for 3D bioprinted organoids. Int J Bioprint, 7(3): 18–36. https://doi.org/10.18063/ijb.v7i3.364

 

 

  1. Koo Y, Kim GH, 2022, Bioprinted hASC‐laden collagen/ HA constructs with meringue‐like macro/micropores. Bioeng Transl Med, 7(3): e10330. https://doi.org/10.1002/btm2.10330

 

 

  1. Sorkio A, Koch L, Koivusalo L, et al., 2018, Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks. Biomaterials, 171: 57–71. https://doi.org/10.1016/j.biomaterials.2018.04.034

 

 

  1. Moncal KK, Ozbolat V, Datta P, et al., 2019, Thermally-controlled extrusion-based bioprinting of collagen. J Mater Sci, 30(5): 55. https://doi.org/10.1007/s10856-019-6258-2

 

 

  1. Pati F, Jang J, Ha D-H, et al., 2014, Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink. Nat Commun, 5(1): 3935. https://doi.org/10.1038/ncomms4935

 

 

 

  1. Gao G, Yonezawa T, Hubbell K, et al., 2015, Inkjet-bioprinted acrylated peptides and PEG hydrogel with human mesenchymal stem cells promote robust bone and cartilage formation with minimal printhead clogging. Biotechnol J, 10(10): 1568–1577. https://doi.org/10.1002/biot.201400635

 

 

  1. Gao G, Schilling AF, Hubbell K, et al., 2015, Improved properties of bone and cartilage tissue from 3D inkjet-bioprinted human mesenchymal stem cells by simultaneous deposition and photocrosslinking in PEG-GelMA. Biotechnol Lett, 37(11): 2349–2355. https://doi.org/10.1007/s10529-015-1921-2

 

 

  1. Armstrong JPK, Burke M, Carter BM, et al., 2016, 3D bioprinting using a templated porous bioink. Adv Healthc Mater, 5(14): 1724–1730. https://doi.org/10.1002/adhm.201600022

 

 

  1. Jia J, Richards DJ, Pollard S, et al., 2014, Engineering alginate as bioink for bioprinting. Acta Biomater, 10(10): 4323–4331. https://doi.org/10.1016/j.actbio.2014.06.034

 

 

  1. Wu Z, Su X, Xu Y, et al., 2016, Bioprinting three-dimensional cell-laden tissue constructs with controllable degradation. Sci Rep, 6(1): 1–10. https://doi.org/10.1038/srep24474

 

 

  1. He H, Li D, Lin Z, et al., 2020, Temperature-programmable and enzymatically solidifiable gelatin-based bioinks enable facile extrusion bioprinting. Biofabrication, 12(4): 045003. https://doi.org/10.1088/1758-5090/ab9906

 

 

  1. Li J, Moeinzadeh S, Kim C, et al., 2023, Development and systematic characterization of GelMA/alginate/PEGDMA/ xanthan gum hydrogel bioink system for extrusion bioprinting. Biomaterials, 293: 121969. https://doi.org/10.1016/j.biomaterials.2022.121969

 

 

  1. Yu K-F, Lu T-Y, Li Y-CE, et al., 2022, Design and synthesis of stem cell-laden keratin/glycol chitosan methacrylate bioinks for 3D bioprinting. Biomacromolecules, 23(7): 2814–2826. https://doi.org/10.1021/acs.biomac.2c00191

 

 

  1. Alcala-Orozco CR, Mutreja I, Cui X, et al., 2020, Design and characterisation of multi-functional strontium-gelatin nanocomposite bioinks with improved print fidelity and osteogenic capacity. Bioprinting, 18: e00073. https://doi.org/10.1016/j.bprint.2019.e00073

 

 

  1. Rousselle A, Ferrandon A, Mathieu E, et al., 2022, Enhancing cell survival in 3D printing of organoids using innovative bioinks loaded with pre-cellularized porous microscaffolds. Bioprinting, 28: e00247. https://doi.org/10.1016/j.bprint.2022.e00247

 

 

  1. Cofiño C, Perez‐Amodio S, Semino CE, et al., 2019, Development of a self‐assembled peptide/methylcellulose‐based bioink for 3D bioprinting. Macromol Mater Eng, 304(11): 1900353. https://doi.org/10.1002/mame.201900353

 

 

  1. Alhattab D, Khan Z, Alshehri S, et al., 2023, 3D bioprinting of ultrashort self-assembling peptides to engineer scaffolds with different matrix stiffness for chondrogenesis. Int J Bioprint, 9(4): 719. https://doi.org/10.18063/ijb.719

 

 

  1. Jeong W, Kim MK, Kang H-W, 2021, Effect of detergent type on the performance of liver decellularized extracellular matrix-based bio-inks. J Tissue Eng, 12: 2041731421997091. https://doi.org/10.1177/2041731421997091

 

 

  1. Panwar A, Tan L, 2016, Current status of bioinks for micro-extrusion-based 3D bioprinting. Molecules, 21(6): 685. https://doi.org/10.3390/molecules21060685

 

 

  1. Xu Z, Huang J, Liu Y, et al., 2023, Extracellular matrix bioink boosts stemness and facilitates transplantation of intestinal organoids as a biosafe Matrigel alternative. Bioeng Transl Med, 8(1): e10327. https://doi.org/10.1002/btm2.10327

 

 

 

  1. Zhang X, Liu Y, Luo C, et al., 2021, Crosslinker-free silk/ decellularized extracellular matrix porous bioink for 3D bioprinting-based cartilage tissue engineering. Mater Sci Eng C, 118: 111388. https://doi.org/10.1016/j.msec.2020.111388

 

 

  1. He Y, Gu Z, Xie M, et al., 2020, Why choose 3D bioprinting? Part II: Methods and bioprinters. Bio-Des Manuf, 3(1): 1–4. https://doi.org/10.1007/s42242-020-00064-w

 

 

  1. Chen J, Zhou D, Nie Z, et al., 2022, A scalable coaxial bioprinting technology for mesenchymal stem cell microfiber fabrication and high extracellular vesicle yield. Biofabrication, 14(1): 015012. https://doi.org/10.1088/1758-5090/ac3b90

 

 

  1. Gong Z, Huang L, Tang X, et al., 2021, Acoustic droplet printing tumor organoids for modeling bladder tumor immune microenvironment within a week. Adv Healthc Mater, 10(22): 2101312. https://doi.org/10.1002/adhm.202101312

 

 

  1. Adine C, Ng KK, Rungarunlert S, et al., 2018, Engineering innervated secretory epithelial organoids by magnetic three-dimensional bioprinting for stimulating epithelial growth in salivary glands. Biomaterials, 180: 52–66. https://doi.org/10.1016/j.biomaterials.2018.06.011

 

 

  1. Pati F, Jang J, Lee JW, et al., 2015, Extrusion bioprinting, in Essentials of 3D Biofabrication and Translation, Academic Press, Boston, 123–152. https://doi.org/10.1016/B978-0-12-800972-7.00007-4

 

 

  1. Shinkar K, Rhode K, 2022, Could 3D extrusion bioprinting serve to be a real alternative to organ transplantation in the future? Ann 3D Print Med, 7: 100066. https://doi.org/10.1016/j.stlm.2022.100066

 

 

  1. Lim W, Kim GJ, Kim HW, et al., 2020, Kappa-Carrageenan-based dual crosslinkable bioink for extrusion type bioprinting. Polymers, 12(10): 2377. https://doi.org/10.3390/polym12102377

 

 

  1. Moxon SR, Cooke ME, Cox SC, et al., 2017, Suspended manufacture of biological structures. Adv Mater, 29(13): 1605594. https://doi.org/10.1002/adma.201605594

 

 

  1. Cooke ME, Rosenzweig DH, 2021, The rheology of direct and suspended extrusion bioprinting. APL Bioeng, 5(1): 011502. https://doi.org/10.1063/5.0031475

 

 

  1. Lee A, Hudson AR, Shiwarski DJ, et al., 2019, 3D bioprinting of collagen to rebuild components of the human heart. Science, 365(6452): 482–487. https://doi.org/10.1126/science.aav9051

 

 

  1. McCormack A, Highley CB, Leslie NR, et al., 2020, 3D printing in suspension baths: Keeping the promises of bioprinting afloat. Trends Biotechnol, 38(6): 584–593. https://doi.org/10.1016/j.tibtech.2019.12.020

 

 

  1. Yeo M, Ha J, Lee H, et al., 2016, Fabrication of hASCs-laden structures using extrusion-based cell printing supplemented with an electric field. Acta Biomater, 38: 33–43. https://doi.org/10.1016/j.actbio.2016.04.017

 

 

  1. Gudapati H, Dey M, Ozbolat I, 2016, A comprehensive review on droplet-based bioprinting: Past, present and future. Biomaterials, 102: 20–42. https://doi.org/10.1016/j.biomaterials.2016.06.012

 

 

  1. Saunders RE, Derby B, 2014, Inkjet printing biomaterials for tissue engineering: Bioprinting. Int Mater Rev, 59(8): 430–448. https://doi.org/10.1179/1743280414Y.0000000040

 

 

 

  1. Li X, Liu B, Pei B, et al., 2020, Inkjet bioprinting of biomaterials. Chem Rev, 120(19): 10793–10833. https://doi.org/10.1021/acs.chemrev.0c00008

 

 

  1. Zhao D, Xu H, Yin J, et al., 2022, Inkjet 3D bioprinting for tissue engineering and pharmaceutics. J Zhejiang Univ Sci A, 23(12): 955–973. https://doi.org/10.1631/2023.A2200569

 

 

  1. Ventura RD, 2021, An overview of laser-assisted bioprinting (LAB) in tissue engineering applications. Med Lasers, 10(2): 76–81. https://doi.org/10.25289/ML.2021.10.2.76

 

 

  1. Dou C, Perez V, Qu J, et al., 2021, A state‐of‐the‐art review of laser‐assisted bioprinting and its future research trends. CBEN, 8(5): 517–534. https://doi.org/10.1002/cben.202000037

 

 

  1. Murphy SV, Atala A, 2014, 3D bioprinting of tissues and organs. Nat Biotechnol, 32(8): 773–785. https://doi.org/10.1038/nbt.2958

 

 

  1. Huang Y, Zhang X-F, Gao G, et al., 2017, 3D bioprinting and the current applications in tissue engineering. Biotechnol J, 12(8): 1600734. https://doi.org/10.1002/biot.201600734

 

 

  1. Zheng Z, Eglin D, Alini M, et al., 2021, Visible light-induced 3D bioprinting technologies and corresponding bioink materials for tissue engineering: A review. Engineering, 7(7): 966–978. https://doi.org/10.1016/j.eng.2020.05.021

 

 

  1. Grix T, Ruppelt A, Thomas A, et al., 2018, Bioprinting perfusion-enabled liver equivalents for advanced organ-on-a-chip applications. Genes, 9(4): 176. https://doi.org/10.3390/genes9040176

 

 

  1. Goodarzi Hosseinabadi H, Dogan E, Miri AK, et al., 2022, Digital light processing bioprinting advances for microtissue models. ACS Biomater Sci Eng, 8(4): 1381–1395. https://doi.org/10.1021/acsbiomaterials.1c01509

 

 

  1. Xie C, Liang R, Ye J, et al., 2022, High-efficient engineering of osteo-callus organoids for rapid bone regeneration within one month. Biomaterials, 288: 121741. https://doi.org/10.1016/j.biomaterials.2022.121741

 

 

  1. Li H, Dai J, Wang Z, et al., 2022, Digital light processing (DLP)‐based (bio)printing strategies for tissue modeling and regeneration. Aggregate, 4(2): e270. https://doi.org/10.1002/agt2.270

 

 

  1. Xu H, Su Y, Liao Z, et al., 2022, Coaxial bioprinting vascular constructs: A review. Eur Polym J, 179: 111549. https://doi.org/10.1016/j.eurpolymj.2022.111549

 

 

  1. Vijayavenkataraman S, Yan W-C, Lu WF, et al., 2018, 3D bioprinting of tissues and organs for regenerative medicine. Adv Drug Deliv Rev, 132: 296–332. https://doi.org/10.1016/j.addr.2018.07.004

 

 

  1. Ng WL, Lee JM, Yeong WY, et al., 2017, Microvalve-based bioprinting – process, bio-inks and applications. Biomater Sci, 5(4): 632–647. https://doi.org/10.1039/C6BM00861E

 

 

  1. Faulkner-Jones A, Greenhough S, King J, et al., 2013, Development of a valve-based cell printer for the formation of human embryonic stem cell spheroid aggregates. Biofabrication, 5(1): 015013. https://doi.org/10.1088/1758-5082/5/1/015013

 

 

  1. Matai I, Kaur G, Seyedsalehi A, et al., 2020, Progress in 3D bioprinting technology for tissue/organ regenerative engineering. Biomaterials, 226: 119536. https://doi.org/10.1016/j.biomaterials.2019.119536

 

 

  1. Lee JM, Sing SL, Zhou M, et al., 2018, 3D bioprinting processes: A perspective on classification and terminology. Int J Bioprint, 4(2): 151. https://doi.org/10.18063/ijb.v4i2.151

 

 

  1. Adine C, Ferreira J, 2020, Bioprinting strategies to engineer functional salivary gland organoids, in Organ Tissue Engineering, Springer International Publishing, Cham, 1–22. https://doi.org/10.1007/978-3-030-18512-1_5-1

 

 

  1. Grebenyuk S, Ranga A, 2019, Engineering organoid vascularization. Front Bioeng Biotechnol, 7: 39. https://doi.org/10.3389/fbioe.2019.00039

 

 

  1. Przepiorski A, Sander V, Tran T, et al., 2018, A simple bioreactor-based method to generate kidney organoids from pluripotent stem cells. Stem Cell Rep, 11(2): 470–484. https://doi.org/10.1016/j.stemcr.2018.06.018

 

 

  1. Zhang Y, Kumar P, Lv S, et al., 2021, Recent advances in 3D bioprinting of vascularized tissues. Mater Design, 199: 109398. https://doi.org/10.1016/j.matdes.2020.109398

 

 

  1. Barrs RW, Jia J, Silver SE, et al., 2020, Biomaterials for bioprinting microvasculature. Chem Rev, 120(19): 10887–10949. https://doi.org/10.1021/acs.chemrev.0c00027

 

 

  1. Jia W, Gungor-Ozkerim PS, Zhang YS, et al., 2016, Direct 3D bioprinting of perfusable vascular constructs using a blend bioink. Biomaterials, 106: 58–68. https://doi.org/10.1016/j.biomaterials.2016.07.038

 

 

  1. Hong S, Kim JS, Jung B, et al., 2019, Coaxial bioprinting of cell-laden vascular constructs using a gelatin–tyramine bioink. Biomater Sci, 7(11): 4578–4587. https://doi.org/10.1039/C8BM00618K

 

 

  1. Barrs RW, Jia J, Ward M, et al., 2021, Engineering a chemically defined hydrogel bioink for direct bioprinting of microvasculature. Biomacromolecules, 22(2): 275–288. https://doi.org/10.1021/acs.biomac.0c00947

 

 

  1. Kolesky DB, Truby RL, Gladman AS, et al., 2014, 3D Bioprinting of vascularized, heterogeneous cell-laden tissue constructs. Adv Mater, 26(19): 3124–3130. https://doi.org/10.1002/adma.201305506

 

 

  1. Skylar-Scott MA, Uzel SGM, Nam LL, et al., 2019, Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels. Sci Adv, 5(9): eaaw2459. https://doi.org/10.1126/sciadv.aaw2459

 

 

  1. Humphreys BD, 2021, Bioprinting better kidney organoids. Nat Mater, 20(2): 128–130. https://doi.org/10.1038/s41563-020-00881-5

 

 

  1. Wang D, Guo Y, Zhu J, et al., 2022, Hyaluronic acid methacrylate/pancreatic extracellular matrix as a potential 3D printing bioink for constructing islet organoids. Acta Biomater, S1742706122003750. https://doi.org/10.1016/j.actbio.2022.06.036

 

 

  1. Zhu B, Wang D, Pan H, et al., 2023, Three-in-one customized bioink for islet organoid: GelMA/ECM/PRP orchestrate pro-angiogenic and immunoregulatory function. Colloid Surf B: Biointerfaces, 221: 113017. https://doi.org/10.1016/j.colsurfb.2022.113017

 

 

  1. Noor N, Shapira A, Edri R, et al., 2019, 3D Printing of personalized thick and perfusable cardiac patches and hearts. Adv Sci, 6(11): 1900344. https://doi.org/10.1002/advs.201900344

 

 

  1. Zhao H, Chen Y, Shao L, et al., 2018, Airflow-assisted 3D bioprinting of human heterogeneous microspheroidal organoids with microfluidic nozzle. Small, 14(39): 1802630. https://doi.org/10.1002/smll.201802630

 

 

  1. He Y, Nie J, Xie M, et al., 2020, Why choose 3D bioprinting? Part III: Printing in vitro 3D models for drug screening. Bio- Des Manuf, 3(3): 160–163. https://doi.org/10.1007/s42242-020-00067-7

 

 

  1. Yan J, Li Z, Guo J, et al., 2022, Organ-on-a-chip: A new tool for in vitro research. Biosens Bioelectron, 216: 114626. https://doi.org/10.1016/j.bios.2022.114626

 

 

  1. Gao G, Ahn M, Cho W-W, et al., 2021, 3D printing of pharmaceutical application: Drug screening and drug delivery. Pharmaceutics, 13(9): 1373. https://doi.org/10.3390/pharmaceutics13091373

 

 

  1. Bouwmeester MC, Bernal PN, Oosterhoff LA, et al., 2021, Bioprinting of human liver‐derived epithelial organoids for toxicity studies. Macromol Biosci, 21(12): 2100327. https://doi.org/10.1002/mabi.202100327

 

 

  1. Skardal A, Murphy SV, Devarasetty M, et al., 2017, Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform. Sci Rep, 7(1): 8837. https://doi.org/10.1038/s41598-017-08879-x

 

 

  1. Jain P, Kathuria H, Dubey N, 2022, Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models. Biomaterials, 287: 121639. https://doi.org/10.1016/j.biomaterials.2022.121639

 

 

  1. Yang H, Sun L, Pang Y, et al., 2021, Three-dimensional bioprinted hepatorganoids prolong survival of mice with liver failure. Gut, 70(3): 567–574. https://doi.org/10.1136/gutjnl-2019-319960

 

 

  1. Kang Y, Datta P, Shanmughapriya S, et al., 2020, 3D bioprinting of tumor models for cancer research. ACS Appl Bio Mater, 3(9): 5552–5573. https://doi.org/10.1021/acsabm.0c00791

 

 

  1. Chen H, Wu Z, Gong Z, et al., 2022, Acoustic bioprinting of patient‐derived organoids for predicting cancer therapy responses. Adv Healthc Mater, 11(13): 2102784. https://doi.org/10.1002/adhm.202102784

 

 

  1. Mao S, Pang Y, Liu T, et al., 2020, Bioprinting of in vitro tumor models for personalized cancer treatment: A review. Biofabrication, 12(4): 042001. https://doi.org/10.1088/1758-5090/ab97c0

 

 

  1. Kim E, Choi S, Kang B, et al., 2020, Creation of bladder assembloids mimicking tissue regeneration and cancer. Nature, 588: 664–669. https://doi.org/10.1038/s41586-020-3034-x

 

 

  1. Schneeberger K, Spee B, Costa P, et al., 2017, Converging biofabrication and organoid technologies: The next frontier in hepatic and intestinal tissue engineering? Biofabrication, 9(1): 013001. https://doi.org/10.1088/1758-5090/aa6121

 

 

  1. Brassard JA, Nikolaev M, Hübscher T, et al., 2021, Recapitulating macro-scale tissue self-organization through organoid bioprinting. Nat Mater, 20(1): 22–29. https://doi.org/10.1038/s41563-020-00803-5

 

 

  1. Clark CC, Yoo KM, Sivakumar H, et al., 2023, Immersion bioprinting of hyaluronan and collagen bioink-supported 3D patient-derived brain tumor organoids. Biomed Mater, 18(1): 015014. https://doi.org/10.1088/1748-605X/aca05d

 

 

  1. Hospodiuk M, Dey M, Sosnoski D, et al., 2017, The bioink: A comprehensive review on bioprintable materials. Biotechnol Adv, 35(2): 217–239. https://doi.org/10.1016/j.biotechadv.2016.12.006

 

 

  1. Liu M, Jiang S, Witman N, et al., 2023, Intrinsically cryopreservable, bacteriostatic, durable glycerohydrogel inks for 3D bioprinting. Matter, 6(3): 983–999. https://doi.org/10.1016/j.matt.2022.12.013

 

 

  1. Serex L, Sharma K, Rizov V, et al., 2021, Microfluidic-assisted bioprinting of tissues and organoids at high cell concentrations. Biofabrication, 13(2): 025006. https://doi.org/10.1088/1758-5090/abca80

 

 

  1. Zhang YS, Pi Q, van Genderen AM, 2017, Microfluidic bioprinting for engineering vascularized tissues and organoids. JoVE, (126): 55957. https://doi.org/10.3791/55957

 

 

  1. Amukarimi S, Mozafari M, 2021, 4D bioprinting of tissues and organs. Bioprinting, 23: e00161. https://doi.org/10.1016/j.bprint.2021.e00161

 

 

  1. Kim SH, Seo YB, Yeon YK, et al., 2020, 4D-bioprinted silk hydrogels for tissue engineering. Biomaterials, 260: 120281. https://doi.org/10.1016/j.biomaterials.2020.120281

 

 

  1. Lee H, 2023, Engineering in vitro models: Bioprinting of organoids with artificial intelligence. Cyborg Bionic Syst, 4: 0018. https://doi.org/10.34133/cbsystems.0018

 

 

 



 

 

 

 

 

 

Conflict of interest
The authors declare no conflict of interest.
Share
Back to top
International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here
Accept