AccScience Publishing / IJB / Volume 9 / Issue 6 / DOI: 10.36922/ijb.0024
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RESEARCH ARTICLE

Electrospinning polyethylene terephthalate glycol

Mohamed H. Hassan1* Abdalla M. Omar1 Evangelos Daskalakis1 Bruce Grieve2 Paulo J.D.S. Bartolo1,3
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1 Department of Mechanical, Aerospace and Civil Engineering, University of Manchester, Manchester, M13 9PL, United Kingdom
2 Department of Electrical and Electronic Engineering, The University of Manchester, Manchester M13 9PL, United Kingdom
3 Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University 639798, Singapore
Submitted: 26 January 2023 | Accepted: 5 March 2023 | Published: 21 June 2023
© 2023 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Polyethylene terephthalate glycol (PETG) is a difficult-to-spin material, and no previous papers have reported the correct conditions to create PETG meshes. To address this issue, a preliminary study on the solubility and electrospinnability of PETG using a range of solvent system was conducted and a Teas graph was established to select the ideal solvent system. Based on these preliminary results, electrospun PETG fibers were produced using a highly volatile binary solvent system consisting of dichloromethane (DCM) and trifluoroacetic acid (TFA). Produced meshes were extensively characterized, and the results demonstrated for the first time the ability of electrospun PETG meshes to support the inoculation and germination of yellow rust spores, thus confirming that PETG is an ideal material to be used for the fabrication of agriculture biosensors. The results also showed that the best solvent split was 85/15 (DCM/TFA).

Keywords
Electrospinning
Biomaterial
Yellow rust
Polyethylene terephthalate glycol
Bioactive
Funding
University of Manchester and UK Research and Innovation (UKRI) through the Engineering and Physical Sciences Research Council (EPSRC) of the UK (grant number: EP/ V011766/1).
References

1. Mota C, Puppi D, Dinucci D, et al., 2011, Dual-scale polymeric constructs as scaffolds for tissue engineering. Materials, 4(3): 527–542. 

2. Dias JR, Sousa A, Augusto A, et al., 2022, Electrospun polycaprolactone (PCL) degradation: An in vitro and in vivo study. Polymers, 14(16): 3397. 

3. Aslan E, Vyas C, Yupanqui MJ, et al., 2011, Preliminary characterization of a polycaprolactone-SurgihoneyRO electrospun mesh for skin tissue engineering. Materials, 15(1): 89. 

4. Huang B, Aslan E, Jiang Z, et al., 2020, Engineered dual-scale poly (ε-caprolactone) scaffolds using 3D printing and rotational electrospinning for bone tissue regeneration. Addit Manuf, 36: 101452. 

5. Motamedi AS, Mirzadeh H, Hajiesmaeilbaigi F, et al., 2017, Effect of electrospinning parameters on morphological properties of PVDF nanofibrous scaffolds. Progr Biomater, 6: 113–123. 

6. Mei Q, Fu R, Ding Y, et al., 2019, Electrospinning of highly dispersed Ni/CoO carbon nanofiber and its application in glucose electrochemical sensor. J Electroanalyt Chem, 847: 113075 %@ 1572–6657. 

7. Yarin AL, Koombhongse S, Reneker DH, 2001, Taylor cone and jetting from liquid droplets in electrospinning of nanofibers. J Appl Phys, 90(9): 4836–4846. 

8. Wu S, Liu J, Qi Y, et al., 2021, Tendon-bioinspired wavy nanofibrous scaffolds provide tunable anisotropy and promote tenogenesis for tendon tissue engineering. Mater Sci Eng C, 126: 112181. 

9. Li Y, Wang J, Qian D, et al., 2021, Electrospun fibrous sponge via short fiber for mimicking 3D ECM. J Nanobiotechnol, 19(1): 131. 

10. Li M, Qiu W, Wang Q, et al., 2022, Nitric oxide-releasing tryptophan-based poly (ester urea) s electrospun composite nanofiber mats with antibacterial and antibiofilm activities for infected wound healing. ACS Appl Mater Interfaces, 14(14): 15911–15926. 

11. Qi Y, Wang C, Wang Q, et al., 2023, A simple, quick, and cost-effective strategy to fabricate polycaprolactone/silk fibroin nanofiber yarns for biotextile-based tissue scaffold application. Eur Polym J, 186: 111863. 

12. Vyas C, Ates G, Aslan E, et al., 2020, Three-dimensional printing and electrospinning dual-scale polycaprolactone scaffolds with low-density and oriented fibers to promote cell alignment. 3D Print Addit Manuf, 7(3): 105–113. 

13. Hunley MT, Long TE, 2008, Electrospinning functional nanoscale fibers: A perspective for the future. Polym Int, 57(3): 385–389. 

14. Tang Y, Lan X, Liang C, et al., 2019, Honey loaded alginate/ PVA nanofibrous membrane as potential bioactive wound dressing. Carbohydr Polym, 219: 113–120. 

15. Stojkovska J, Djurdjevic Z, Jancic I, et al., 2018, Comparative in vivo evaluation of novel formulations based on alginate and silver nanoparticles for wound treatments. J Biomater Appl, 32(9): 1197–1211. 

16. Yang X, Wang Y, Qing X, 2019, A flexible capacitive sensor based on the electrospun PVDF nanofiber membrane with carbon nanotubes. Sens Actuators A Phys, 299: 111579. 

17. Hussain Z, Ullah S, Yan J, et al., 2022, Electrospun tannin-rich nanofibrous solid-state membrane for wastewater environmental monitoring and remediation. Chemosphere, 307: 135810. 

18. Townsend-Nicholson A, Jayasinghe SN, 2006, Cell electrospinning: A unique biotechnique for encapsulating living organisms for generating active biological microthreads/ scaffolds. Biomacromolecules, 7(12): 3364–3369. 

19. Hong J, Yeo M, Yang GH, et al., 2019, Cell-electrospinning and its application for tissue engineering. Int J Mol Sci, 20(24): 6208. 

20. Liu F, Vyas C, Poologasundarampillai G, et al., 2018, Structural evolution of PCL during melt extrusion 3D printing. Macromol Mater Eng, 303(2): 1700494. 

21. Bartolo P, Malshe A, Ferraris E, et al., 2022, 3D bioprinting: Materials, processes, and applications. CIRP Ann, 71(2): 577–597. 

22. Hassan MH, Omar AM, Daskalakis E, et al., 2022, Multi-layer biosensor for pre-symptomatic detection of Puccinia strifformis, the causal agent of yellow rust. Biosensors, 12(10): 829. 

23. Hassan MH, Omar AM, Daskalakis E, et al., 2020, Preliminary studies on the suitability of PETG for 4D printing applications, in 7th International Conference of Materials and Manufacturing Engineering (ICMMEN 2020), 6. 

24. Hassan MH, Omar AM, E. Daskalakis, et al., 2020, The potential of polyethylene terephthalate glycol as biomaterial for bone tissue engineering. Polymers, 12(12): 3045. 

25. Paralı L, Koç M, Yıldız Z, 2022, 2D/3D direct writing of thermoplastics through electrohydrodynamic printing. Polym Sci Series A, 64(5): 559–572. 

26. Luo C, Nangrejo M, Edirisinghe M, 2010, A novel method of selecting solvents for polymer electrospinning. Polymer, 51(7): 1654–1662. 

27. Barton AF, 2017, CRC Handbook of Solubility Parameters and Other Cohesion Parameters, Routledge. 

28. Heseltine PL, Ahmed J, Edirisinghe M, 2018, Developments in pressurized gyration for the mass production of polymeric fibers. Macromol Mater Eng, 303(9): 1800218.

29. Luo C, Stride E, Edirisinghe M, 2012, Mapping the influence of solubility and dielectric constant on electrospinning polycaprolactone solutions. Macromolecules, 45(11): 4669–4680. 

30. Burke J, 1984, Solubility Parameters: Theory and Application. The AIC book and paper group annual, 3: 13–58. 

31. Paszkiewicz S, Szymczyk A, Pawlikowska D, et al., 2017, Synthesis and characterization of poly (ethylene terephthalate-co-1, 4-cyclohexanedimethylene terephtlatate)-block-poly (tetramethylene oxide) copolymers. RSC Adv, 7(66): 41745–41754. 

32. Cole K, Guevremont J, Ajji A, et al., 1994, Characterization of surface orientation in poly (ethylene terephthalate) by front-surface reflection infrared spectroscopy. Appl Spectrosc, 48(12): 1513–1521. 

33. Alexiou VF, Mathioudakis GN, Andrikopoulos KS, et al., 2020, Poly (ethylene terephthalate) carbon-based nanocomposites: A crystallization and molecular orientation study. Polymers, 12(11): 2626. 

34. Ciera L, Beladjal L, Almeras X, et al., 2014, Morphological and material properties of polyethyleneterephthalate (PET) fibres with spores incorporated. Fibres Text East Eur, 22(4): 29–36.

 

 

 

 

 

 

Conflict of interest
The authors declare no conflict of interest.
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing