AccScience Publishing / IJB / Volume 5 / Issue 2 / DOI: 10.18063/ijb.v5i2.197
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RESEARCH ARTICLE

The mussel-inspired assisted apatite mineralized on PolyJet material for artificial bone scaffold

Yi-Wen Chen1,2† ,  Hsin-Yuan Fang1,3,4† ,  Ming-You Shie1,5 ,  Yu-Fang Shen6,7*
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1 Three-dimensional Printing Medical Research Center, China Medical University Hospital, China Medical University, Taichung, Taiwan
2 Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan
3 Department of Thoracic Surgery, China Medical University Hospital, Taichung, Taiwan
4 School of Medicine, China Medical University, Taichung, Taiwan
5 School of Dentistry, China Medical University, Taichung, Taiwan
6 Three-dimensional Printing Medical Research Institute, Asia University, Taichung, Taiwan
7 Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan
†These authors contributed equally to this work.
IJB 2019, 5(2), 197 https://doi.org/10.18063/ijb.v5i2.197
Published online: 11 July 2019
© 2019 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
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Abstract

With the development of three-dimensional (3D) printing, many commercial 3D printing materials have been applied in the fields of biomedicine and medical. MED610 is a clear, biocompatible PolyJet material that is medically certified for bodily contact. In this study, the polydopamine (PDA)/hydroxyapatite (HA) coating was added to the printed MED610 objects to evaluate its physical properties, cell proliferation, cell morphology, and alkaline phosphatase expression level. The results show that the PDA/HA coating helps printed objects to enhance the hardness, biocompatibility, and osteogenic differentiation potential. We expect that PDA/HA coatings contribute to the applicability of MED610 in biomedical and medical applications.

Keywords
Three-dimensional printing
Polydopamine
Hydroxyapatite
MED610
Osteogenic differentiation
PolyJet technology
References

1. Rengier F, Mehndiratta A, vonTengg-Kobligk H, et al., 2010, 3D Printing Based on Imaging Data: Review of Medical Applications. Int J Comput Assist Radiol Surg, 5:335-41. DOI 10.1007/s11548-010-0476-x. 
2. Ventola CL, 2014, Medical Applications for 3D Printing: Current and Projected Uses. P T, 39:704-11. 
3. Ciocca L, Mingucci R, Gassino G, et al., 2007, CAD/CAM Ear Model and Virtual Construction of the Mold. J Prosthet Dent, 98:339-43. DOI 10.1016/S0022-3913(07)60116-4. 
4. He J, Li D, Lu B, et al., 2006, Custom Fabrication of Composite Tibial Hemi-knee Joint Combining CAD/CAE/ CAM Techniques. Proc Inst Mech Eng H, 220:823-30. DOI 10.1243/09544119JEIM207. 
5. Dai KR, Yan MN, Zhu ZA, et al., 2007, Computer-aided Custom-made Hemipelvic Prosthesis Used in Extensive Pelvic Lesions. J Arthroplasty, 22:981-6. DOI 10.1016/j. arth.2007.05.002. 
6. Zopf DA, Hollister SJ, Nelson ME, et al., 2013, Bioresorbable Airway Splint Created with a Three-dimensional Printer. N Engl J Med, 368:2043-5. DOI 10.1056/NEJMc1206319. 
7. Cho HR, Roh TS, Shim KW, et al., 2015, Skull Reconstruction with Custom Made Three-dimensional Titanium Implant. Arch Craniofac Surg, 16:11-16. DOI 10.7181/acfs.2015.16.1.11. 
8. Jackson B, 2017, 3D Printed Hip Puts Teenager Back on her Feet. Available from: https://www.3dprintingindustry.com/ news/materialise-3d-printed-hip-implant-gets-patient-back-feet-126139. 
9. Zhao X, Wang X, Sun Y, et al., 2018, Use of Three-dimensional Printing to Fabricate First a Pelvic Model and Then a Semi-pelvic Prosthesis with Sacrum : A Case Report. Biomed J Sci Tech Res, 4:1-4. DOI 10.26717/BJSTR.2018.04.001060. 
10. Jacek B, Maciej P, Tomasz P, et al., 2018, 3D Printed Models in Mandibular Reconstruction with Bony Free Flaps. J Mater Sci Mater Med, 29:23. DOI 10.1007/s10856-018-6029-5. 
11. Gopinathan J, Noh I, 2018, Recent Trends in Bioinks for 3D Printing. Biomater Res, 22:11. DOI 10.1186/s40824-018- 0122-1. 
12. Kaushik NK, Kaushik N, Pardeshi S, et al., 2015, Biomedical and Clinical Importance of Mussel-inspired Polymers and Materials. Mar Drugs, 13:6792-817. DOI 10.3390/ md13116792. 
13. Lee H, Dellatore SM, Miller WM, et al., 2007, Mussel-inspired Surface Chemistry for Multifunctional Coatings. Science, 318:426-30. DOI 10.1126/science.1147241. 
14. Kang SM, Hwang NS, Yeom J, et al., 2012, One-step Multipurpose Surface Functionalization by Adhesive Catecholamine. Adv Funct Mater, 22:2949-55. DOI 10.1002/ adfm.201200177. 
15. Yang K, Lee JS, Kim J, et al., 2012, Polydopamine-mediated Surface Modification of Scaffold Materials for Human Neural Stem Cell Engineering. Biomaterials, 33:6952-64. DOI 10.1016/j.biomaterials.2012.08.001. 
16. You I, Kang SM, Byun Y, et al., 2011, Enhancement of Blood Compatibility of Poly(Urethane) Substrates by Mussel-inspired Adhesive Heparin Coating. Bioconjug Chem, 22:1264-9. DOI 10.1021/bc2000534. 
17. Kim TG, Lee H, Jang Y, et al., 2009, Controlled Release of Paclitaxel from Heparinized Metal Stent Fabricated by Layer-by-layer Assembly of Polylysine and Hyaluronic Acid-g-poly(Lactic-co-glycolic acid) Micelles Encapsulating Paclitaxel. Biomacromolecules, 10:1532-9. DOI 10.1021/ bm900116r. 
18. Ku SH, Park CB, 2010, Human Endothelial Cell Growth on Mussel-inspired Nanofiber Scaffold for Vascular Tissue Engineering. Biomaterials, 31:9431-7. DOI 10.1016/j. biomaterials.2010.08.071. 
19. Wu C, Han P, Liu X, et al., 2014, Mussel-inspired Bioceramics with Self-assembled Ca-P/Polydopamine Composite Nanolayer: Preparation, Formation Mechanism, Improved Cellular Bioactivity and Osteogenic Differentiation of Bone Marrow Stromal Cells. Acta Biomater, 10:428-38. DOI 10.1016/j.actbio.2013.10.013. 
20. Cheng YL, Chen YW, Wang K, et al., 2016, Enhanced Adhesion and Differentiation of Human Mesenchymal Stem Cell Inside Apatite-mineralized/Poly(Dopamine)-Coated Poly(ε-Caprolactone) Scaffolds by Stereolithography. J Mater Chem B, 4:6307-15. DOI 10.1039/c6tb01377e. 
21. Lin CC, Fu SJ, 2016, Osteogenesis of Human Adipose-derived Stem Cells on Poly(Dopamine)-coated Electrospun Poly(Lactic Acid) Fiber Mats. Mater Sci Eng C Mater Biol Appl, 58:254-63. DOI 10.1016/j.msec.2015.08.009. 
22. Tripathi BP, Dubey NC, Subair R, et al., 2016, Enhanced Hydrophilic and Antifouling Polyacrylonitrile Membrane with Polydopamine Modified Silica Nanoparticles. RSC Adv, 6:4448-57. DOI 10.1039/c5ra22160a. 
23. Steeves AJ, Atwal A, Schock SC, et al., 2016, Evaluation of the Direct Effects of Poly(Dopamine) on the in vitro Response of Human Osteoblastic Cells. J Mater Chem B, 4:3145-56. DOI 10.1039/c5tb02510a.

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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing
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