Dear Colleagues,

Brachytherapy is not only the oldest but also the first truly successful form of radiotherapy. More than a century after its introduction, it continues to provide the most favorable dose distribution among all radiation techniques when applied with precision and expertise. By placing the radiation source directly inside or near the tumor, brachytherapy allows for the delivery of curative doses while minimizing exposure to surrounding healthy tissue.

As imaging, navigation, and radiobiology continue to advance, brachytherapy is entering a new era, the era of interventional radiotherapy. This approach combines precise targeting with minimally invasive delivery, embodying the principles of personalization and organ preservation to achieve optimal tumor control and improve quality of life.

Interventional radiotherapy has demonstrated remarkable effectiveness across a broad spectrum of malignancies, including prostate cancer, breast cancer, head and neck tumors, liver malignancies, and gynecological cancers.

We warmly invite contributions that expand the horizons of this evolving field and foster innovations that redefine how brachytherapy is planned, delivered, and integrated into comprehensive, patient-centered cancer care.