Xiangya Hospital Movement System Research Center, Central South University, Changsha, ChinaAging and regeneration
Professor and Senior Researcher (Second-Level Research Fellow), Xiangya Hospital Movement System Injury Repair Research Center, Xiangya Hospital, Central South University; Deputy Director, National Clinical Research Center for Geriatric Disorders, Hunan Province
Director, Amy Medical (Háimì) Hunan Key Laboratory; Deputy Director, Ministry of Education Key Laboratory of Geriatric Joint Disease Research at Xiangya Hospital
Recipient of the National Science Fund for Distinguished Young Scholars and National Excellent Young Scientists Fund
Recognized as a National High Level Overseas Youth Expert and National Youth Post Talent, with provincial leadership roles including Vice Chair, Hunan Youth Science and Technology Association and Central South University Young Scholars Association
Recognized in Stanford/Elsevier Global Top 2% Scientists lists in 2021, 2023 and 2024
Awarded multiple prestigious scientific honors:
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First Prize, Chinese Medical Association Basic Orthopedic Research Award
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Shulan Medicine Young Scientist Award
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First Class Prize, Hunan Provincial Natural Science Award
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Young Scientist Award, American Orthopaedic Research Society
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Dear Colleagues,
In recent years, organoid technology, as a groundbreaking advancement in three-dimensional in vitro biological modeling, has provided an unprecedentedly precise tool for aging research. Organoids can closely mimic the structure and function of human organs, demonstrating unique advantages in elucidating the mechanisms of age-related diseases, drug screening, and the development of personalized therapeutic strategies. With the integration of single-cell sequencing, gene editing, and biomaterials technologies, organoid models are increasingly used to explore changes in the aging microenvironment, cellular metabolic dysregulation, and epigenetic regulation. These advancements are paving new paths for delaying aging and intervening in geriatric diseases.
This special issue focuses on the innovative applications of organoid technology in aging research, aiming to gather the latest achievements in basic research, technological development, and clinical translation. We cordially invite scholars worldwide to submit original research articles, reviews, or forward-looking perspectives to jointly advance breakthroughs in the field of anti-aging through organoid technology.
Prof. Hui Xie
Guest Editor