Dear Colleagues,

Three-dimensional (3D) bioprinting has demonstrated remarkable potential in fabricating biomimetic scaffolds and cell-laden constructs through precise spatiotemporal control of biologically relevant materials (e.g., biomaterials, living cells, growth factors), heralding a revolutionary change in bioengineering. This Special Issue aims to present the state-of-the-art developments, primary challenges, forward-looking visions, and the most promising trends in 3D bioprinting, encompassing 3D-bioprinted functional tissue-engineering scaffolds, medical implants, physiologically relevant tissue constructs, disease models, in vitro models, and their clinical applications. It illustrates how functional biomaterials, biomimetic structural designs, and advanced bioprinting strategies are revolutionizing the recapitulation of functional tissues and paving the way for personalized therapies and patient-specific treatments.

Designed to publish cutting-edge research, this Special Issue will benefit a broad readership, including biomedical researchers, materials scientists, engineers, clinicians, physicians, and other professionals interested in 3D bioprinting. We particularly encourage submissions that bridge fundamental research with translational and clinical applications.

The editors cordially invite submissions of cutting-edge research papers and state-of-the-art review papers focusing on (but not limited to) the following topics:

• Novel design of biomaterials and structures for 3D printed tissue-engineering scaffolds or living tissue constructs;
• Advanced bioprinting techniques and biofabrication methods;
• Structural, mechanical, and biological analysis of 3D-printed scaffolds and living tissue constructs;
• 3D bioprinting for the engineering of in vitro models or organ-on-a-chip systems;
• Clinical research on 3D-printed medical implants