AccScience Publishing / IJB / Volume 6 / Issue 1 / DOI: 10.18063/ijb.v6i1.245
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RESEARCH ARTICLE

Bioprinting of Multimaterials with Computer-aided Design/Computer-aided Manufacturing

J. M. Lee1 S. L. Sing1 W. Y. Yeong*
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1 Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore
Published: 22 January 2020
© 2020 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Multimaterials deposition, a distinct advantage in bioprinting, overcomes material’s limitation in hydrogel-based bioprinting. Multimaterials are deposited in a build/support configuration to improve the structural integrity of threedimensional bioprinted construct. A combination of rapid cross-linking hydrogel has been chosen for the build/support setup. The bioprinted construct was further chemically cross-linked to ensure a stable construct after print. This paper also proposes a file segmentation and preparation technique to be used in bioprinting for printing freeform structures.

Keywords
Three-dimensional bioprinting
Bioprinting
Hydrogel
Three-dimensional printing
Rapid prototyping
Additive manufacturing
Computer-aided design
Support structure generation
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing