AccScience Publishing / IJB / Volume 5 / Issue 2 / DOI: 10.18063/ijb.v5i2.238
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METHODS

A methodology to develop a vascular geometry for in vitro cell culture using additive manufacturing

Laurène Lenoir1 Frédéric Segonds1* Kim-Anh Nguyen2,3 Pablo Bartolucci2,4
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1 Product Design and Innovation Laboratory (LCPI), Arts et Métiers ParisTech, Paris, 151 Boulevard de l’Hôpital, 75013, France
2 EFS UITC, Center Felix Reyes, Research team 2, Créteil, 5 rue Gustave Eiffel, 94017, France
3 Imagine Institute, Paris, 24 Boulevard du Montparnasse, 75015, France
4 Sickle Cell Referent, Créteil, Center Mondor Hospital, 94017, France
Published: 29 July 2019
© 2019 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Today, additive manufacturing (AM) is implemented in medical industry and profoundly revolutionizes this area. This approach consists of producing parts by additions of layers of successive materials and offers advantages in terms of rapidity, complexity of parts, competitive costs that can be exploited and can lead to a significant advancement in biological research. Everything becomes technically feasible and gives way to a “techno-centered” approach. Many parameters must be controlled in this field, so it is necessary to be guided for the development of such a product. This article aims to present a state of the art of existing design methodologies focused on AM to create medical devices. Finally, a development method is proposed that consists of producing vascular geometry using AM, based on patient data, designed for cell culture in vitro studies.

Keywords
Innovation
Design
Additive manufacturing
Biology
Medical device
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing