AccScience Publishing / IJB / Volume 4 / Issue 1 / DOI: 10.18063/ijb.v1i1.119
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PERSPECTIVE ARTICLE

3D printing for drug manufacturing: A perspective on the future of pharmaceuticals

Eric Lepowsky1 Savas Tasoglu1,2,3,4,5*
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1 Department of Mechanical Engineering, University of Connecticut, Storrs, CT, USA
2 Department of Biomedical Engineering, University of Connecticut, Storrs, CT, USA
3 Institute of Materials Science, University of Connecticut, Storrs, CT, USA
4 Institute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, CT, USA
5 The Connecticut Institute for the Brain and Cognitive Sciences, University of Connecticut, Storrs, CT, USA
© Invalid date by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Since a three-dimensional (3D) printed drug was first approved by the Food and Drug Administration in 2015, there has been a growing interest in 3D printing for drug manufacturing. There are multiple 3D printing methods – including selective laser sintering, binder deposition, stereolithography, inkjet printing, extrusion-based printing, and fused deposition modeling – which are compatible with printing drug products, in addition to both polymer filaments and hydrogels as materials for drug carriers. We see the adaptability of 3D printing as a revolutionary force in the pharmaceutical industry. Release characteristics of drugs may be controlled by complex 3D printed geometries and architectures. Precise and unique doses can be engineered and fabricated via 3D printing according to individual prescriptions. On-demand printing of drug products can be implemented for drugs with limited shelf life or for patient-specific medications, offering an alternative to traditional compounding pharmacies. For these reasons, 3D printing for drug manufacturing is the future of pharmaceuticals, making personalized medicine possible while also transforming pharmacies.

Keywords
three-dimensional (3D) printing
drug dosing and delivery
drug release characteristics
hydrogels
personalized medicine
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International Journal of Bioprinting, Electronic ISSN: 2424-8002 Print ISSN: 2424-7723, Published by AccScience Publishing