AccScience Publishing / GTM / Volume 3 / Issue 3 / DOI: 10.36922/gtm.3313
BRIEF REPORT

Non-surgical treatment of periodontal intrabony defects using rhPDGF-BB-saturated collagen sponges

Thaer Alqadoumi1 Fatemeh SamavatiJame2,3 Noor Daras4 Muhammad H. A. Saleh2*
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1 Department of Periodontics, School of Dentistry, University of Loma Linda, Loma Linda, California, United States of America
2 Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America
3 Department of Periodontics and Oral Medicine, School of Dentistry, Nova Southeastern University, Fort Lauderdale, United States of America
4 Department of General Dentistry, School of Dentistry, University of Southern California, Los Angeles, California, United States of America
Global Translational Medicine 2024, 3(3), 3313 https://doi.org/10.36922/gtm.3313
Submitted: 29 March 2024 | Accepted: 28 May 2024 | Published: 4 September 2024
© 2024 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

This study evaluated the use of a collagen sponge soaked with recombinant human platelet-derived growth factor-BB for non-surgical treatment of intrabony defects in the esthetic zone. After 6 months of follow-up, this technique demonstrated positive outcomes, including reduced probing depth and improved attachment levels, indicative of periodontal regeneration. The notable improvement in clinical parameters indicates that this approach could be a viable non-surgical alternative with clinical outcomes comparable to current surgical procedures.

Keywords
Periodontal regeneration
Esthetic
Recombinant human platelet-derived growth factor-BB
Funding
None.
Conflict of interest
The authors declare no conflict of interest.
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Global Translational Medicine, Electronic ISSN: 2811-0021 Published by AccScience Publishing